Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691654 | 0.86 | SLC6A4 (0.39) | SLC6A4HTR2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL1375267 | 0.85 | MAPT (0.42) | SLC6A4HTR2AKCNH2ALDH1A1SLC6A2 | |
| SCHEMBL5583577 | 0.82 | HTR2A (0.42) | SLC6A4HTR2AKCNH2ALDH1A1LMNA | |
| SCHEMBL5583613 | 0.82 | POLB (0.41) | SLC6A4HTR2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL231083 | 0.81 | DPP4 (0.43) | SLC6A4HTR2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL21630261 | 0.81 | FFAR1 (0.42) | SLC6A4HTR2AKCNH2L3MBTL1LMNA | |
| SCHEMBL2333939 | 0.80 | EGFR (0.39) | SLC6A4HTR2AKCNH2ALDH1A1HTR1A | |
| SCHEMBL2264473 | 0.79 | CYP1A2 (0.38) | SLC6A4HTR2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL8441722 | 0.78 | ALDH1A1 (0.38) | SLC6A4HTR2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL10355072 | 0.78 | PTPRZ1 (0.40) | SLC6A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099764-A2 | NOVEL PYRIMIDINE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI HOLDINGS CO., LTD. (KR) | 2011-08-18 | — | — | WO | disclosed |