Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.35 |
| ▸ | RELA | Q04206 | 3/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606677 | 1.00 | MAPT (0.37) | MAPTHPGDEP300NFKB1NFKB2 | |
| SCHEMBL10603623 | 0.84 | PTGER4 (0.35) | HPGDPTGIRTRPA1MEN1ALDH1A1 | |
| SCHEMBL10605053 | 0.84 | PTGER4 (0.35) | HPGDPTGIRTRPA1MEN1ALDH1A1 | |
| SCHEMBL10619854 | 0.83 | PTGIR (0.49) | MAPTHPGDEP300NFKB1NFKB2 | |
| SCHEMBL10619857 | 0.83 | PTGIR (0.49) | MAPTHPGDEP300NFKB1NFKB2 | |
| SCHEMBL10619378 | 0.78 | TRPA1 (0.43) | MAPTHPGDEP300PTGIRTRPA1 | |
| SCHEMBL10619386 | 0.78 | TRPA1 (0.43) | MAPTHPGDEP300PTGIRTRPA1 | |
| SCHEMBL9546147 | 0.76 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL9546150 | 0.76 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL9546036 | 0.76 | PTGER4 (0.30) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131441-B1 | 5-ALKYLIDENE-2-HALO-4-SUBSTITUTED-2-CYCLOPENTENONE AND PROCESS FOR PRODUCTION THEREOF | TEIJIN LIMITED (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4689426-A | ANTITUMOR AGENTS, VIRCIDES, BACTERICIDES | TEIJIN LIMITED (JP) | 1987-08-25 | — | — | US | disclosed |