Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619386 | 1.00 | TRPA1 (0.43) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10622134 | 0.90 | TRPA1 (0.47) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10622139 | 0.90 | TRPA1 (0.47) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10619396 | 0.87 | TRPA1 (0.36) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10622137 | 0.81 | TRPA1 (0.59) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10622141 | 0.81 | TRPA1 (0.59) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10704802 | 0.78 | TRPA1 (0.60) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10624155 | 0.78 | TRPA1 (0.60) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10606677 | 0.78 | MAPT (0.37) | TRPA1HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL10606689 | 0.78 | MAPT (0.37) | TRPA1HPGDMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766147-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |