Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PGR | P06401 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.56 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606768 | 1.00 | TDP1 (0.61) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL11246339 | 0.92 | MAPT (0.65) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL10606264 | 0.91 | TDP1 (0.72) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL10606259 | 0.91 | TDP1 (0.72) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL7809090 | 0.87 | NR1I2 (0.74) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL7828952 | 0.87 | NR1I2 (0.74) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL27288111 | 0.87 | NR1I2 (0.74) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL10605710 | 0.86 | TDP1 (0.59) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL10605713 | 0.86 | TDP1 (0.59) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL11010391 | 0.84 | NR1I2 (0.76) | TDP1NR1I2HSD17B10ALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150458-B1 | CEPHEM COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4705784-A | ORAL DRUGS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0150458-A2 | Cephem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1985-08-07 | — | — | EP | disclosed |