Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564784 | 0.84 | ALDH1A1 (0.57) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL38917 | 0.75 | CA2 (0.55) | ALDH1A1ALOX15LMNACYP2C9TYR | |
| SCHEMBL1176397 | 0.74 | ALDH1A1 (0.67) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL31146788 | 0.74 | ALDH1A1 (0.67) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL9169045 | 0.74 | ALDH1A1 (0.56) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL5692411 | 0.73 | ALDH1A1 (0.55) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL10607444 | 0.72 | ALDH1A1 (0.35) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL1237149 | 0.71 | ALDH1A1 (0.69) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL2721125 | 0.71 | ALDH1A1 (0.69) | ALDH1A1ALOX15LMNANR1I2CYP2C9 | |
| SCHEMBL28145382 | 0.70 | HSPA5 (0.51) | ALDH1A1ALOX15LMNANR1I2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233140-B1 | LUBRICANT ADDITIVES CONTAINING SULPHUR AND NITROGEN | CIBA-GEIGY AG (CH) | 1989-11-08 | — | — | EP | disclosed |