Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 17/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405698 | 0.98 | FFAR2 (0.65) | FFAR2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL68169 | 0.98 | FFAR2 (0.65) | FFAR2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL1677207 | 0.98 | FFAR2 (0.65) | FFAR2AKR1C3AKR1C2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9862939 | 0.96 | FFAR2 (0.62) | FFAR2AKR1C3AKR1C2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9862940 | 0.96 | FFAR2 (0.62) | FFAR2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL27563008 | 0.96 | FFAR2 (0.62) | FFAR2AKR1C3AKR1C2MEN1KMT2A | |
| Benzil SCHEMBL27273806 | 0.86 | CES2 (0.59) | FFAR2LMNA | |
| SCHEMBL7525386 | 0.84 | FFAR2 (0.53) | FFAR2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL10916853 | 0.83 | AKR1C3 (0.51) | FFAR2AKR1C3AKR1C2 | |
| SCHEMBL9871299 | 0.82 | FFAR2 (0.61) | FFAR2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163094-B1 | PREPARATION OF OPTICALLY-ACTIVE ALPHA-SUBSTITUTED PHENYLACETIC ACIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-02 | — | — | EP | disclosed |
| EP-0163094-A2 | Preparation of optically-active alpha-substituted phenylacetic acids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-04 | — | — | EP | disclosed |