Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366282 | 0.81 | TDP1 (0.49) | ALDH1A1KMT2AMAPTTDP1SMN1; SMN2 | |
| SCHEMBL6366286 | 0.81 | TDP1 (0.49) | ALDH1A1KMT2AMAPTTDP1SMN1; SMN2 | |
| SCHEMBL6371566 | 0.81 | TDP1 (0.49) | ALDH1A1KMT2AMAPTTDP1SMN1; SMN2 | |
| SCHEMBL10603968 | 0.77 | KMT2A (0.69) | SCN2AGAAPKMALDH1A1KMT2A | |
| SCHEMBL9770478 | 0.76 | SCN2A (0.54) | SCN2AGAAPKMALDH1A1MAPT | |
| SCHEMBL3045885 | 0.75 | MAPT (0.68) | GAAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL10643494 | 0.75 | GAA (0.58) | GAAALDH1A1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL29365592 | 0.74 | ALDH1A1 (0.47) | SCN2AGAAPKMALDH1A1KMT2A | |
| SCHEMBL4352529 | 0.74 | LTA4H (0.52) | GAAALDH1A1KMT2AMAPTTDP1 | |
| SCHEMBL4352532 | 0.74 | LTA4H (0.52) | GAAALDH1A1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113910-B1 | ISOCARBOSTYRIL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-4526893-A | Pharmaceuticals | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0113910-A1 | Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1984-07-25 | — | — | EP | disclosed |