Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839926 | 0.87 | MEN1 (0.69) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL3048962 | 0.86 | GPR174 (0.72) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL12678535 | 0.86 | MEN1 (0.67) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL11111056 | 0.85 | ALDH1A1 (0.80) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL2955123 | 0.84 | HPGD (0.50) | CYP1A2MAPTALDH1A1RAB9AL3MBTL1 | |
| Phenacetin SCHEMBL18894356 | 0.83 | KMT2A (1.00) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL12891619 | 0.83 | MEN1 (0.49) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL23280 | 0.83 | KMT2A (1.00) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL10802880 | 0.83 | ALDH1A1 (0.77) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL17033976 | 0.83 | ALDH1A1 (0.77) | KMT2AMEN1LMNACYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113910-B1 | ISOCARBOSTYRIL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-4526893-A | Pharmaceuticals | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0113910-A1 | Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1984-07-25 | — | — | EP | disclosed |