SCHEMBL10608935

SCHEMBL10608935

O=P(O)(O)C(O)(Cc1cc[nH]n1)P(=O)(O)O

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FDPS P14324 15/20 0.51
BTN3A1 O00481 1/20 0.42
PDE3A Q14432 1/20 0.42
GGPS1 O95749 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24759829 0.73
SCHEMBL23701927 0.73 PGK1 (0.50)
Phosphoric Acid SCHEMBL2026928 0.72 CYP2C19 (0.34) FDPS
SCHEMBL9657473 0.71 FDPS (0.47) FDPSBTN3A1PDE3AGGPS1
SCHEMBL9656816 0.69 FDPS (0.50) FDPSBTN3A1PDE3AGGPS1
SCHEMBL9657440 0.69 FDPS (0.50) FDPSGGPS1
SCHEMBL16061663 0.69
SCHEMBL1904611 0.68 FDPS (1.00) FDPSBTN3A1PDE3AGGPS1
SCHEMBL7161477 0.68 FDPS (0.51) FDPSBTN3A1PDE3AGGPS1
SCHEMBL18338449 0.67 MEN1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0275821-A1 Substituted alkanediphosphonic acids CIBA-GEIGY AG (CH) 1988-07-27 EP claimed
EP-0275821-A1 Substituted alkanediphosphonic acids CIBA-GEIGY AG (CH) 1988-07-27 EP disclosed