Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | ACACA | Q13085 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10608889 | 0.99 | ACP1 (0.49) | ACP1ACACAMAPTALDH1A1HPGD | |
| SCHEMBL10612832 | 0.89 | ACP1 (0.60) | ACP1ACACAMAPTALDH1A1HPGD | |
| SCHEMBL10610813 | 0.89 | HPGD (0.49) | ACP1ACACAMAPTALDH1A1HPGD | |
| SCHEMBL10613513 | 0.88 | ACP1 (0.61) | ACP1MAPTALDH1A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL10612258 | 0.87 | ACP1 (0.60) | ACP1MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL10612321 | 0.86 | ACP1 (0.51) | ACP1ACACAMAPTALDH1A1HPGD | |
| SCHEMBL10610688 | 0.86 | ALDH1A1 (0.61) | ACP1MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL10609452 | 0.85 | USP2 (0.58) | MAPTALDH1A1KDM4EMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL10613447 | 0.85 | HPGD (0.56) | ACP1ACACAMAPTALDH1A1HPGD | |
| SCHEMBL10612869 | 0.85 | LMNA (0.50) | ACP1ACACAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728647-A | Amides derived from quinoline, and anxiolytic compositions containing them | RHONE-POULENC SANTE (FR) | 1988-03-01 | — | — | US | disclosed |