Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070472 | 0.96 | TDP1 (0.50) | TDP1TSHRUSP2HTTMEN1 | |
| Ethylene Glycol SCHEMBL6756784 | 0.94 | TDP1 (0.50) | TDP1TSHRUSP2HTTMEN1 | |
| SCHEMBL25069255 | 0.92 | TDP1 (0.45) | TDP1TSHRUSP2HTTMEN1 | |
| SCHEMBL10607246 | 0.90 | TDP1 (0.55) | TDP1TSHRUSP2HTTMEN1 | |
| SCHEMBL7181445 | 0.90 | TSHR (0.56) | TDP1TSHRUSP2HTTMEN1 | |
| SCHEMBL8617152 | 0.90 | TSHR (0.56) | TDP1TSHRUSP2HTTMEN1 | |
| SCHEMBL80455 | 0.90 | TDP1 (0.52) | TDP1TSHRUSP2HTTLPAR1 | |
| SCHEMBL27948520 | 0.88 | TDP1 (0.42) | TDP1TSHRUSP2HTTMEN1 | |
| SCHEMBL2721241 | 0.87 | TDP1 (0.47) | TDP1TSHRUSP2HTTMEN1 | |
| SCHEMBL4806772 | 0.87 | TSHR (0.57) | TDP1TSHRUSP2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084966-B1 | AQUEOUS COMPOSITIONS CONTAINING OVERBASED MATERIALS | The Lubrizol Corporation (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4468339-A | AND SOLUBILIZER WHICH IS REACTION OF CARBOXYLIC ACID ACYLATING AGENT WITH HYDROCARBON SUBSTITMENT AND HYDROXYAMINE | THE LUBRIZOL CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0084966-A2 | Aqueous compositions containing overbased materials | The Lubrizol Corporation (US) | 1983-08-03 | — | — | EP | disclosed |