SCHEMBL1070472

SCHEMBL1070472

CCCCOC(C)COC(C)COCCCO

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 1/20 0.45
USP2 O75604 1/20 0.41
LPAR1 Q92633 4/20 0.37
LPAR3 Q9UBY5 4/20 0.37
LPAR2 Q9HBW0 1/20 0.37
HTT P42858 2/20 0.37
MEN1 O00255 1/20 0.37
THRB P10828 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
SPHK1 Q9NYA1 1/20 0.37
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
TLR2 O60603 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10608964 0.96 TDP1 (0.48) TDP1TSHRUSP2LPAR1LPAR3
Ethylene Glycol SCHEMBL6756784 0.91 TDP1 (0.50) TDP1TSHRUSP2LPAR1LPAR3
SCHEMBL431994 0.91 TDP1 (0.53) TDP1TSHRUSP2LPAR1LPAR3
SCHEMBL230477 0.91 TDP1 (0.53) TDP1TSHRUSP2LPAR1LPAR3
SCHEMBL28728615 0.91 TDP1 (0.53) TDP1TSHRUSP2LPAR1LPAR3
SCHEMBL429585 0.91 TDP1 (0.53) TDP1TSHRUSP2LPAR1LPAR3
SCHEMBL28729672 0.91 TDP1 (0.53) TDP1TSHRUSP2LPAR1LPAR3
SCHEMBL25069255 0.89 TDP1 (0.45) TDP1TSHRUSP2LPAR1LPAR3
SCHEMBL7181445 0.87 TSHR (0.56) TDP1TSHRUSP2LPAR1LPAR3
SCHEMBL8617152 0.87 TSHR (0.56) TDP1TSHRUSP2LPAR1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8501314-B2 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-08-06 US claimed
US-20110111212-A1 Method of Applying An Anti-Corrosion And/Or Adhesion Promoting Coating To A Metal And Resulting Coated Metal MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-05-12 US claimed
EP-2147041-B1 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MAT INC (US) 2017-08-23 EP disclosed
EP-2152720-B1 HYDROXYL-FUNCTIONAL CARBAMOYL ORGANOSILICON COMPOUNDS OF LOW VOC AND HAP GENERATING POTENTIAL, ANTI-CORROSION AND/OR ADHESION PROMOTING COATING COMPOSITIONS CONTAINING SAME, ENVIRONMENTALLY BENIGN METHOD OF COATING METAL THEREWITH AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MAT INC (US) 2015-07-29 EP disclosed
US-8575292-B2 Hydroxyl-functional carbamoyl organosilicon compounds of low VOC and HAP generating potential, anti-corrosion and/or adhesion promoting coating composition containing same, environmentally benign method of coating metal therewith and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-11-05 US disclosed
US-8501314-B2 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-08-06 US disclosed
US-20110111212-A1 Method of Applying An Anti-Corrosion And/Or Adhesion Promoting Coating To A Metal And Resulting Coated Metal MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-05-12 US disclosed
US-7875318-B2 Hydrolyzing partially or completely hydrolyzed silane possessing one or more hydroxyl groups; bis-(hydroxyethyl)aminopropyltriethoxysilane; chromium free; nontoxic; environmentally friendly MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-25 US disclosed
EP-2152720-A1 HYDROXYL-FUNCTIONAL CARBAMOYL ORGANOSILICON COMPOUNDS OF LOW VOC AND HAP GENERATING POTENTIAL, ANTI-CORROSION AND/OR ADHESION PROMOTING COATING COMPOSITIONS CONTAINING SAME, ENVIRONMENTALLY BENIGN METHOD OF COATING METAL THEREWITH AND RESULTING COATED METAL Momentive Performance Materials Inc. (US) 2010-02-17 EP disclosed
EP-2147041-A2 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL Momentive Performance Materials Inc. (US) 2010-01-27 EP disclosed
WO-2008133907-A1 HYDROXYL-FUNCTIONAL CARBAMOYL ORGANOSILICON COMPOUNDS OF LOW VOC AND HAP GENERATING POTENTIAL, ANTI-CORROSION AND/OR ADHESION PROMOTING COATING COMPOSITIONS CONTAINING SAME, ENVIRONMENTALLY BENIGN METHOD OF COATING METAL THEREWITH AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-11-06 WO disclosed
WO-2008133916-A2 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-11-06 WO disclosed
US-20080268162-A1 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-30 US disclosed
US-20080268146-A1 Hydroxyl-functional carbamoyl organosilicon compounds of low VOC and HAP generating potential, anti-corrosion and/or adhesion promoting coating composition containing same, enviromenttally beign method of coating metal therewith and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268146-A1 Hydroxyl-functional carbamoyl organosilicon compounds of low VOC and HAP generating potential, anti-corrosion and/or adhesion promoting coating composition containing same, enviromenttally beign method of coating metal therewith and resulting coated metal HAAO, HAO2, COMT TDP1 3474/4885TSHR 4594/4885USP2 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.