Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609661 | 0.83 | MEN1 (0.61) | TDP1SMN1; SMN2TSHRHPGDKDM4E | |
| SCHEMBL10612832 | 0.82 | ACP1 (0.60) | TDP1POLBHPGDKDM4EALDH1A1 | |
| SCHEMBL10610688 | 0.82 | ALDH1A1 (0.61) | TDP1POLBSMN1; SMN2TSHRHPGD | |
| SCHEMBL10613513 | 0.81 | ACP1 (0.61) | TDP1POLBHPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10613447 | 0.81 | HPGD (0.56) | TDP1POLBSMN1; SMN2TSHRHPGD | |
| SCHEMBL10608957 | 0.81 | ACP1 (0.50) | TDP1POLBSMN1; SMN2TSHRHPGD | |
| Hydrochloric Acid SCHEMBL10612258 | 0.81 | ACP1 (0.60) | TDP1POLBHPGDKDM4EALDH1A1 | |
| SCHEMBL10610813 | 0.80 | HPGD (0.49) | TDP1POLBSMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL10608889 | 0.80 | ACP1 (0.49) | TDP1POLBSMN1; SMN2TSHRHPGD | |
| SCHEMBL10612321 | 0.80 | ACP1 (0.51) | TDP1SMN1; SMN2TSHRHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728647-A | Amides derived from quinoline, and anxiolytic compositions containing them | RHONE-POULENC SANTE (FR) | 1988-03-01 | — | — | US | disclosed |