Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | XDH | P47989 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 4/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7242379 | 0.94 | ALDH1A1 (0.57) | ALDH1A1XDHMAPTCYP2C9SLCO1B3 | |
| SCHEMBL28320416 | 0.88 | ALDH1A1 (0.56) | ALDH1A1XDHMAPTCYP2C9SLCO1B3 | |
| SCHEMBL21722487 | 0.86 | CYP2C9 (0.61) | ALDH1A1XDHMAPTCYP2C9SLCO1B3 | |
| SCHEMBL10609388 | 0.86 | ABCB1 (0.58) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31162964 | 0.85 | ALDH1A1 (0.71) | ALDH1A1XDHMAPTCYP2C9SLCO1B3 | |
| SCHEMBL14427922 | 0.85 | ALDH1A1 (0.45) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17179811 | 0.81 | ALDH1A1 (1.00) | ALDH1A1XDHMAPTHPGDKDM4E | |
| SCHEMBL5264350 | 0.81 | ALDH1A1 (0.41) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6078672 | 0.81 | ALDH1A1 (0.41) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22529289 | 0.80 | ALDH1A1 (0.41) | ALDH1A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988008256-A1 | DIHYDROFLAVONOL DERIVATIVES USEFUL AS SWEETENERS | UNIVERSITY PATENTS, INC. (US) | 1988-11-03 | — | — | WO | disclosed |