Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10608985 | 0.94 | ALDH1A1 (0.67) | ALDH1A1XDHCYP3A4ALOX15MAPT | |
| SCHEMBL14427922 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AHIF1ANFKB1 | |
| SCHEMBL6078672 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ANFKB1HPGD | |
| SCHEMBL5264350 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ANFKB1HPGD | |
| SCHEMBL22529289 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28320416 | 0.82 | ALDH1A1 (0.56) | ALDH1A1XDHCYP3A4ALOX15MAPT | |
| SCHEMBL3668993 | 0.81 | PIN1 (0.39) | ALDH1A1XDHMEN1KMT2AHIF1A | |
| SCHEMBL3669336 | 0.81 | PIN1 (0.39) | ALDH1A1XDHMEN1KMT2AHIF1A | |
| SCHEMBL21738208 | 0.80 | CYP3A4 (0.56) | ALDH1A1XDHCYP3A4ALOX15MAPT | |
| SCHEMBL10609388 | 0.80 | ABCB1 (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030100775-A1 | Synthesis of 4alpha-arylepicatechins | MARS INCORPORATED | 2003-05-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100775-A1 | Synthesis of 4alpha-arylepicatechins | FABP4, TEAD4, FABP7 | ALDH1A1 617/4885XDH 2202/4885CYP3A4 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.