⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858613 | 0.77 | — | — | |
| SCHEMBL483475 | 0.77 | — | — | |
| SCHEMBL9278930 | 0.75 | — | — | |
| SCHEMBL11131758 | 0.74 | — | — | |
| SCHEMBL9546009 | 0.70 | — | — | |
| SCHEMBL252653 | 0.70 | TSHR (0.43) | — | |
| SCHEMBL9240554 | 0.69 | — | — | |
| SCHEMBL5505075 | 0.69 | — | — | |
| SCHEMBL876357 | 0.69 | — | — | |
| Hydrogen Sulfide SCHEMBL28851311 | 0.69 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886864-A | Silymethylene methacrylate contact lens and polymer | JOHN D. MCCARRY (US) | 1989-12-12 | — | — | US | disclosed |
| US-4780516-A | WETTABILITY; HARDNESS | BIOMEDICS | 1988-10-25 | — | — | US | disclosed |
| EP-0194277-A4 | ALKYLSILANE CONTACT LENS AND POLYMER. | MC CARRY JOHN D (US) | 1987-02-03 | — | — | EP | disclosed |
| EP-0194277-A1 | ALKYLSILANE CONTACT LENS AND POLYMER | MC CARRY, John D. (US) | 1986-09-17 | — | — | EP | disclosed |
| WO-1986001219-A1 | ALKYLSILANE CONTACT LENS AND POLYMER | MC CARRY, JOHN, D. (US) | 1986-02-27 | — | — | WO | disclosed |