SCHEMBL5505075

SCHEMBL5505075

C=C(CO[Si](C)(C)C)C(=O)OC([SiH3])CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL876357 0.79
SCHEMBL5800587 0.77
SCHEMBL9546009 0.76
SCHEMBL17023657 0.73 ALDH1A1 (0.44)
SCHEMBL252653 0.72 TSHR (0.43)
SCHEMBL483475 0.72
SCHEMBL2692355 0.71
SCHEMBL9278930 0.71
Hydrogen Sulfide SCHEMBL28851311 0.71 TSHR (0.42)
SCHEMBL19614797 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115039021-A Contact lens and manufacturing method thereof 尹景泰 2022-09-09 CN claimed
CN-108699244-B Silicone monomer, composition for producing silicone hydrogel lens comprising same, and silicone hydrogel lens 茵洛有限公司 2020-12-22 CN claimed
CN-102639636-A Method for increasing ion transmission rate of contact lens NOVARTIS AG 2012-08-15 CN claimed
CN-102246086-A Hydrogel contact lenses KOREA RES INST CHEM TECH 2011-11-16 CN claimed
WO-2001009249-A1 MOISTURE CURABLE ACRYLIC SEALANTS SCHNEE-MOREHEAD, INC. (US) 2001-02-08 WO claimed
EP-0075004-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES McCARRY, John D. (US) 1983-03-30 EP claimed
WO-1982003397-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES MCCARRY JOHN D (US) 1982-10-14 WO claimed
CN-111253533-B Silicone fluid composition, silicone fluid lens, and method for producing silicone fluid lens 晶硕光学股份有限公司 2023-06-13 CN disclosed
CN-109690360-B Method for producing contact lenses having durable lubricious coatings thereon 爱尔康公司 2023-04-25 CN disclosed
CN-109416414-B Increased hardness central optic zone in soft contact lenses for astigmatism correction 庄臣及庄臣视力保护公司 2023-03-10 CN disclosed
CN-115697545-A Antifouling coating composition 佐敦有限公司 2023-02-03 CN disclosed
CN-115039021-A Contact lens and manufacturing method thereof 尹景泰 2022-09-09 CN disclosed
CN-109689714-B Silicone hydrogels comprising N-alkylmethacrylamides and contact lenses made therefrom 庄臣及庄臣视力保护公司 2022-07-05 CN disclosed
CN-1376270-A Surface treatment of medical devices iwth reactive hydrophilic polymers BAUSCH & LOMB (US) 2002-10-23 CN disclosed
CN-1351629-A Surface-treatment of silicone medical devices comprising intermediate carbon coating and graft polymerization BAUSCH & LOMB INCORP (US) 2002-05-29 CN disclosed
CN-1351631-A Plasma surface treatment of silicone hydrogel contact lenses with a flexible carbon coating BAUSCH & LOMB INCORP (US) 2002-05-29 CN disclosed
CN-1351630-A Surface treatment for silicone hydrogel contact lenses comprising hydrophilic polymer chains at tached to an intermediate carbon coating BAUSCH & LOMB INCORP (US) 2002-05-29 CN disclosed
CN-1327002-A Surface processed plastic product and surface processing method TORAY INDUSTRIES (JP) 2001-12-19 CN disclosed
EP-0075004-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES McCARRY, John D. (US) 1983-03-30 EP disclosed
WO-1982003397-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES MCCARRY JOHN D (US) 1982-10-14 WO disclosed