SCHEMBL483475

SCHEMBL483475

C=C(C(=O)OC([SiH3])CC)C(O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9240554 0.90
SCHEMBL9278930 0.85
SCHEMBL6014616 0.80
SCHEMBL11131758 0.78
SCHEMBL5858613 0.77
SCHEMBL10609232 0.77
SCHEMBL9546009 0.74
SCHEMBL8466921 0.72 TSHR (0.37)
SCHEMBL5505075 0.72
SCHEMBL252653 0.70 TSHR (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116327738-A Patch containing cannabidiol 宝泓生医股份有限公司 2023-06-27 CN claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
CN-102675561-B silicone hydrogel with high water content FAR EASTERN NEW CENTURY CORPORATION (CN) 2014-10-22 CN claimed
CN-102675561-A Silicone hydrogel with high water content FAR EASTERN NEW CENTURY CORP 2012-09-19 CN claimed
CN-102675658-A Method for preparing polysiloxane hydrogel with high moisture content FAR EASTERN NEW CENTURY CORP 2012-09-19 CN claimed
CN-102464744-A Chlorinated polymers that enhance wettability of silicone hydrogels, silicone hydrogels comprising the same, and ophthalmic articles made therefrom FAR EASTERN NEW CENTURY CORP 2012-05-23 CN claimed
EP-0219312-B1 Improved fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORP (US) 1995-12-20 EP claimed
EP-0401990-B1 Prepolymers useful in biomedical devices BAUSCH & LOMB (US) 1995-08-02 EP claimed
WO-1994023314-A1 IMPROVED ITACONATE COPOLYMERIC COMPOSITIONS FOR CONTACT LENSES POLYMER TECHNOLOGY CORPORATION (US) 1994-10-13 WO claimed
WO-1993023773-A1 PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL CIBA-GEIGY AG (CH) 1993-11-25 WO claimed
US-4996275-A With silicon group-substituted addition polymers; oxygen permeability, hydrophilic, deposit resistance POLYMER TECHNOLOGY CORPORATION (US) 1991-02-26 US claimed
US-4686267-A Fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1987-08-11 US claimed
EP-0219312-A2 Improved fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1987-04-22 EP claimed
EP-0075004-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES McCARRY, John D. (US) 1983-03-30 EP claimed
WO-1982003397-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES MCCARRY JOHN D (US) 1982-10-14 WO claimed
JP-61187904-A None JP disclosed
EP-0075004-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES McCARRY, John D. (US) 1983-03-30 EP disclosed
WO-1982003397-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES MCCARRY JOHN D (US) 1982-10-14 WO disclosed