Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905774 | 1.00 | IGF1R (0.59) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL10610096 | 1.00 | IGF1R (0.59) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL10606127 | 1.00 | IGF1R (0.59) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL9026676 | 0.98 | IGF1R (0.61) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL10607218 | 0.92 | IGF1R (0.58) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL11551178 | 0.84 | IGF1R (0.59) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL7328450 | 0.83 | PNMT (0.61) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL11332990 | 0.80 | PNMT (0.70) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL22333700 | 0.80 | SIGMAR1 (0.61) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL7008253 | 0.80 | IGF1R (0.65) | IGF1RALOX15PNMTTAAR1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162208-B1 | NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |