Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10612239 | 0.81 | CYP1A2 (0.40) | RAB9ASMN1; SMN2CYP1A2CYP2C19TNFRSF1A | |
| SCHEMBL10609291 | 0.80 | TRPM8 (0.39) | RAB9ASMN1; SMN2TRPM8MAPTNPC1 | |
| SCHEMBL10609288 | 0.80 | TRPM8 (0.39) | RAB9ASMN1; SMN2TRPM8MAPTNPC1 | |
| SCHEMBL10612698 | 0.74 | HMGCR (0.33) | RAB9ASMN1; SMN2TRPM8CYP1A2ALDH1A1 | |
| SCHEMBL9726403 | 0.73 | TRPM8 (0.42) | RAB9ASMN1; SMN2TRPM8NPC1PKM | |
| SCHEMBL9726405 | 0.72 | TRPM8 (0.39) | RAB9ASMN1; SMN2TRPM8NPC1PKM | |
| SCHEMBL9726401 | 0.72 | TRPM8 (0.39) | RAB9ASMN1; SMN2TRPM8NPC1PKM | |
| SCHEMBL10612687 | 0.72 | HMGCR (0.39) | — | |
| SCHEMBL10610695 | 0.71 | HMGCR (0.45) | SMN1; SMN2CYP1A2CYP2C19TNFRSF1AMAPT | |
| SCHEMBL9726587 | 0.70 | TRPM8 (0.43) | RAB9ASMN1; SMN2TRPM8NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |