Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609288 | 1.00 | TRPM8 (0.39) | TRPM8RAB9ASMN1; SMN2NPC1PKM | |
| SCHEMBL10612229 | 0.81 | AOC3 (0.30) | AOC3 | |
| SCHEMBL10609294 | 0.80 | RAB9A (0.41) | TRPM8RAB9ASMN1; SMN2NPC1PKM | |
| SCHEMBL9726403 | 0.78 | TRPM8 (0.42) | TRPM8RAB9ASMN1; SMN2NPC1PKM | |
| SCHEMBL10609399 | 0.72 | HMGCR (0.40) | RAB9ASMN1; SMN2PKMTP53LMNA | |
| SCHEMBL10610689 | 0.72 | HMGCR (0.40) | RAB9ASMN1; SMN2PKMTP53LMNA | |
| SCHEMBL9726405 | 0.71 | TRPM8 (0.39) | TRPM8RAB9ASMN1; SMN2NPC1PKM | |
| SCHEMBL9726401 | 0.71 | TRPM8 (0.39) | TRPM8RAB9ASMN1; SMN2NPC1PKM | |
| SCHEMBL9726587 | 0.69 | TRPM8 (0.43) | TRPM8RAB9ASMN1; SMN2NPC1PKM | |
| SCHEMBL28766859 | 0.69 | TRPM8 (0.41) | TRPM8RAB9ASMN1; SMN2NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |