Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 19/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610242 | 0.86 | PRMT5 (0.33) | PRMT5WDR77HTR2C | |
| SCHEMBL10613231 | 0.84 | HTR2C (0.36) | HTR2CSLC6A4HTR2B | |
| SCHEMBL10610803 | 0.84 | PDK2 (0.34) | PRMT5WDR77 | |
| SCHEMBL10610280 | 0.84 | PDK2 (0.34) | PRMT5WDR77SLC6A4 | |
| SCHEMBL10610328 | 0.79 | — | — | |
| SCHEMBL10610241 | 0.75 | GPR55 (0.38) | HTR2C | |
| SCHEMBL10612016 | 0.72 | PDK2 (0.32) | — | |
| SCHEMBL10612462 | 0.71 | ALDH1A1 (0.34) | — | |
| SCHEMBL10609817 | 0.71 | GPR55 (0.33) | — | |
| SCHEMBL10610433 | 0.70 | AAK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271550-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988000197-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYE^´SZETI GYA^´R (HU) | 1988-01-14 | — | — | WO | disclosed |