Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610752 | 0.84 | MEN1 (0.42) | MAPK14ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9799075 | 0.83 | MAPK14 (0.35) | MAPK14ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9726603 | 0.80 | HSD17B10 (0.38) | MAPK14ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL10612928 | 0.78 | USP2 (0.39) | MAPK14ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL9726423 | 0.75 | HSD17B10 (0.36) | MAPK14ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9726417 | 0.75 | HSD17B10 (0.36) | MAPK14ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9726984 | 0.74 | TRPA1 (0.34) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9726463 | 0.73 | HSD17B10 (0.39) | MAPK14ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL10610747 | 0.73 | MAPK14 (0.36) | MAPK14ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9799071 | 0.72 | MAPK14 (0.35) | MAPK14ALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |