Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609785 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL10386318 | 0.93 | ALDH1A1 (0.54) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL10386316 | 0.93 | ALDH1A1 (0.54) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL10455031 | 0.87 | PDE4A (0.57) | ALDH1A1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL10455030 | 0.87 | PDE4A (0.57) | ALDH1A1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL10610489 | 0.84 | TAS1R3 (0.50) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL10610492 | 0.84 | TAS1R3 (0.50) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL10386519 | 0.83 | CYP1A2 (0.58) | ALDH1A1LMNAL3MBTL1PDE4APDE4B | |
| SCHEMBL10386517 | 0.83 | CYP1A2 (0.58) | ALDH1A1LMNAL3MBTL1PDE4APDE4B | |
| SCHEMBL9367554 | 0.82 | CA12 (0.62) | ALDH1A1LMNAPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753934-A | Acrylic acid heterocyclic amides, fungicidal compositions and use | CELAMERCK GMBH & CO. KG (DE) | 1988-06-28 | — | — | US | disclosed |