SCHEMBL10612

SCHEMBL10612

c1ccc2c(c1)CNC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351494 1.00
SCHEMBL13590042 1.00 PNMT (0.65)
SCHEMBL29361921 0.97 PNMT (0.62)
Hydrochloric Acid SCHEMBL29371527 0.97 PNMT (0.62)
Hydrochloric Acid SCHEMBL27941016 0.97 PNMT (0.62)
Hydrochloric Acid SCHEMBL4702076 0.97 PNMT (0.62)
SCHEMBL28633341 0.97 PNMT (0.62)
Ammonia Solution, Strong SCHEMBL16296133 0.97 PNMT (0.62)
Methane SCHEMBL11147358 0.97 PNMT (0.62)
Methane SCHEMBL27536218 0.97 PNMT (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5063 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435068-B2 Anthelmintic compounds ELANCO ANIMAL HEALTH GMBH (DE) 2025-10-07 US claimed
CN-115209883-B Novel cell metabolism regulating compound and use thereof 新月生物科学 2025-05-20 CN claimed
EP-4003524-B1 ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS ELANCO ANIMAL HEALTH GMBH (DE) 2025-04-09 EP claimed
US-20250092010-A1 DIHYDRO-2H-ISOINDOLE ESTER COMPOUND SHANGHAI MAIUS PHARMACEUTICAL CO. LTD. (CN) 2025-03-20 US claimed
EP-3634959-B1 QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS ELANCO ANIMAL HEALTH GMBH (DE) 2025-02-26 EP claimed
US-20240383893-A1 Hydroxamic Acid Compound Having ENPP1 Inhibitory Activity and Use Thereof HAIHE BIOPHARMA CO., LTD. (CN) 2024-11-21 US claimed
US-12071404-B2 Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides UCB PHARMA GMBH (DE) 2024-08-27 US claimed
EP-4400493-A1 HYDROXAMIC ACID COMPOUND HAVING ENPP1 INHIBITORY ACTIVITY AND USE THEREOF Haihe Biopharma Co., Ltd. (CN) 2024-07-17 EP claimed
EP-4385983-A1 DIHYDRO-2H-ISOINDOLE ESTER COMPOUND Shanghai Maius Pharmaceutical Co. Ltd. (CN) 2024-06-19 EP claimed
CN-117980293-A Hydroxamic acid compound with ENPP1 inhibitory activity and application thereof 上海海和药物研究开发股份有限公司 2024-05-03 CN claimed
EP-0566069-A1 Tachykinin receptor antagonists, isoquinolones and their production TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-20 EP claimed
EP-0529778-A1 Optically active isoindoline derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP claimed
EP-0525629-A2 5-membered heterocycles, process for their preparation and medicaments containing them Dr. Karl Thomae GmbH (DE) 1993-02-03 EP claimed
WO-1992014453-A1 COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN ARC 1, INC. (US) 1992-09-03 WO claimed
EP-0186187-B1 CEPHALOSPORIN DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-02-26 EP claimed
US-4960779-A Pyrrole derivatives, and pharmaceutical compositions which contain them and pharmacological methods of use RHONE-POULENC SANTE (FR) 1990-10-02 US claimed
US-4632918-A Novel β-lactam antibiotics BAYER AKTIENGESELLSCHAFT (DE) 1986-12-30 US claimed
EP-0056144-A1 Carboxylic acid derivatives, their preparation and use as pharmaceuticals Dr. Karl Thomae GmbH (DE) 1982-07-21 EP claimed
US-4165319-A Isoindoline pigments CIBA-GEIGY CORPORATION (US) 1979-08-21 US claimed
US-4105657-A PRODUCTION OF N-ALKYL DERIVATIVES OF CYCLIC ALKYLENIMINES BASF AKTIENGESELLSCHAFT (DE) 1978-08-08 US claimed