Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL16296133

N.c1ccc2c(c1)CNC2

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.62
CD44 P16070 1/20 0.62
MAOB P27338 1/20 0.62
OXTR P30559 1/20 0.48
HTR2C P28335 1/20 0.48
RYR2 Q92736 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 1/20 0.40
PRCP P42785 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351494 0.97
SCHEMBL10612 0.97
SCHEMBL13590042 0.97 PNMT (0.65) PNMTCD44MAOBOXTRHTR2C
SCHEMBL29361921 0.93 PNMT (0.62) PNMTCD44MAOBOXTRHTR2C
SCHEMBL28633341 0.93 PNMT (0.62) PNMTCD44MAOBOXTRHTR2C
Hydrochloric Acid SCHEMBL4702076 0.93 PNMT (0.62) PNMTCD44MAOBOXTRHTR2C
Water SCHEMBL28256098 0.93 PNMT (0.62) PNMTCD44MAOBOXTRHTR2C
Methane SCHEMBL11147358 0.93 PNMT (0.62) PNMTCD44MAOBOXTRHTR2C
Hydrochloric Acid SCHEMBL29371527 0.93 PNMT (0.62) PNMTCD44MAOBOXTRHTR2C
Hydrochloric Acid SCHEMBL27941016 0.93 PNMT (0.62) PNMTCD44MAOBOXTRHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3008045-B1 ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS ANTABIO SAS (FR) 2018-05-09 EP disclosed
US-9914712-B2 Antibacterial thiazolecarboxylic acids ANTABIO SAS (FR) 2018-03-13 US disclosed
US-20160272601-A1 Antibacterial Thiazolecarboxylic Acids ANTABIO SAS (FR) 2016-09-22 US disclosed
EP-3008045-A1 ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS Antabio SAS (FR) 2016-04-20 EP disclosed
WO-2014198849-A1 ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS ANTABIO SAS (FR) 2014-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160272601-A1 Antibacterial Thiazolecarboxylic Acids ME1, TALDO1, COASY PNMT 3615/4885CD44 4697/4885MAOB 599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.