SCHEMBL10613045

SCHEMBL10613045

C=CCNC1C=COC1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16417782 0.71
SCHEMBL6550896 0.69
SCHEMBL4819975 0.68
SCHEMBL5572717 0.61 ALDH1A1 (0.37)
SCHEMBL7191306 0.60 ALDH1A1 (0.30)
SCHEMBL11051410 0.60
SCHEMBL17199870 0.58 CA12 (0.33)
SCHEMBL6422888 0.58 KMT2A (0.31)
SCHEMBL25802800 0.58 IDO1 (0.36) IDO1
SCHEMBL14781802 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4725617-A HYPOTENSIVE AGENT, GLAUCOMA TREATMENT RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1988-02-16 US claimed
EP-0192393-A2 Alkylaminofuranone derivatives RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1986-08-27 EP claimed
US-4725617-A HYPOTENSIVE AGENT, GLAUCOMA TREATMENT RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1988-02-16 US disclosed