⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731827 | 0.76 | — | — | |
| SCHEMBL6550896 | 0.71 | — | — | |
| SCHEMBL7341958 | 0.71 | — | — | |
| SCHEMBL5572717 | 0.71 | ALDH1A1 (0.37) | — | |
| SCHEMBL2227804 | 0.68 | — | — | |
| SCHEMBL6288737 | 0.68 | — | — | |
| SCHEMBL10613045 | 0.68 | IDO1 (0.31) | — | |
| SCHEMBL27371640 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL1477646 | 0.64 | — | — | |
| SCHEMBL8753089 | 0.64 | PRSS1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365174-B2 | Azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20070042974-A1 | Nozel azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1661904-A1 | NOVEL AZALIDE AND AZALACTAM DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
| EP-0090231-B1 | PROCESS FOR THE PREPARATION OF 3-ALKYL-2,5-DIHYDROFURAN-2-ONES | BASF Aktiengesellschaft (DE) | 1985-11-13 | — | — | EP | disclosed |
| EP-0090231-A1 | Process for the preparation of 3-alkyl-2,5-dihydrofuran-2-ones | BASF Aktiengesellschaft (DE) | 1983-10-05 | — | — | EP | disclosed |