Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096502 | 1.00 | ATM (0.34) | ATMTSHRALDH1A1ALOX15CYP2D6 | |
| SCHEMBL11149075 | 0.88 | KCNN4 (0.38) | TSHRALDH1A1ALOX15CYP2D6CYP3A4 | |
| SCHEMBL27537640 | 0.80 | CYP2C19 (0.36) | ATMTSHRALDH1A1ALOX15CCR6 | |
| SCHEMBL6384303 | 0.78 | CES1 (0.40) | ATMALDH1A1ALOX15CYP2D6CYP3A4 | |
| SCHEMBL11469023 | 0.72 | MAPK1 (0.35) | ATMTSHRALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL692202 | 0.72 | CYP1A2 (0.38) | TSHRALDH1A1ALOX15CYP2D6CYP3A4 | |
| SCHEMBL31285836 | 0.72 | LTA4H (0.39) | ATMTSHRALDH1A1ALOX15CYP2D6 | |
| SCHEMBL8580387 | 0.72 | ALDH1A1 (0.39) | TSHRALDH1A1ALOX15CCR6KCNH2 | |
| SCHEMBL5356083 | 0.71 | ATM (0.33) | ATMTSHRCYP2D6CYP3A4DRD2 | |
| SCHEMBL8755619 | 0.69 | ALDH1A1 (0.41) | ATMTSHRALDH1A1ALOX15CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761494-A | Preparation of cyanomethyl esters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0049577-B1 | ALPHA-CYANOPHENOXYBENZYLAMINE DERIVATIVES, PROCESSES FOR PREPARING THEM, AND THEIR USE AS INTERMEDIATES FOR THE PREPARATION OF PYRETHROID INSECTICIDES | ICI AUSTRALIA LIMITED (AU) | 1984-04-11 | — | — | EP | disclosed |
| US-4420614-A | CHEMICAL INTERMEDIATES, PYRETHROIDS | ICI AUSTRALIA LIMITED (AU) | 1983-12-13 | — | — | US | disclosed |
| EP-0049577-A1 | Alpha-cyanophenoxybenzylamine derivatives, processes for preparing them, and their use as intermediates for the preparation of pyrethroid insecticides | ICI AUSTRALIA LIMITED (AU) | 1982-04-14 | — | — | EP | disclosed |