Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544999 | 0.83 | TP53 (0.51) | HPGDTDP1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10611083 | 0.83 | HPGD (0.42) | HPGDTDP1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL1531067 | 0.79 | HPGD (0.67) | HPGDTDP1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL1531071 | 0.78 | HPGD (0.57) | HPGDTDP1ALDH1A1BACE1LMNA | |
| SCHEMBL1195997 | 0.73 | ERN1 (0.46) | HPGDTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1196682 | 0.72 | MEN1 (0.47) | HPGDTDP1KMT2AL3MBTL1MEN1 | |
| SCHEMBL1196990 | 0.71 | HPGD (0.51) | HPGDTDP1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7736980 | 0.71 | FFAR4 (0.38) | HPGDTDP1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL16276206 | 0.70 | ADRA2C (0.51) | HPGDTDP1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10612821 | 0.70 | L3MBTL1 (0.51) | HPGDALDH1A1KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4793948-A | ANTICARCINOGENIC AGENTS | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0232788-A1 | Bile acid derivatives and production thereof | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1987-08-19 | — | — | EP | disclosed |