Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL152741 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1MAPK1SMN1; SMN2NQO2 | |
| SCHEMBL146384 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL7675155 | 0.80 | SMN1; SMN2 (0.54) | KDM4EALDH1A1MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL31466840 | 0.78 | MCL1 (0.57) | KDM4EALDH1A1MAPK1SMN1; SMN2NQO2 | |
| SCHEMBL29741516 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL3760438 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL8818405 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1MAPK1SMN1; SMN2NQO2 | |
| SCHEMBL9812714 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL8967325 | 0.76 | PKM (0.55) | KDM4EALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL15703117 | 0.75 | MEN1 (0.50) | KDM4EALDH1A1SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63310843-A | — | — | None | — | — | JP | disclosed |
| JP-S63310843-A | 4-HALOGENO-1-LOWER ALKOXY-2-METHYLNAPHTHALENE AND PRODUCTION THEREOF | EEZAI KAGAKU KK | 1988-12-19 | — | — | JP | disclosed |