Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741516 | 1.00 | KDM4E (0.56) | KDM4ESMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL401290 | 0.83 | KDM4E (0.56) | KDM4ESMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL146384 | 0.83 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL30503944 | 0.83 | SMN1; SMN2 (0.61) | KDM4ESMN1; SMN2ALDH1A1MAPK1IDO1 | |
| SCHEMBL3670609 | 0.83 | SMN1; SMN2 (0.61) | KDM4ESMN1; SMN2ALDH1A1MAPK1IDO1 | |
| SCHEMBL11887380 | 0.81 | IDO1 (0.45) | KDM4ESMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL11727739 | 0.79 | MAPK1 (0.49) | KDM4ESMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL10098946 | 0.79 | KDM4E (0.40) | KDM4ESMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL3747262 | 0.78 | SMN1; SMN2 (0.54) | KDM4ESMN1; SMN2ALDH1A1MAPK1IDO1 | |
| SCHEMBL5651922 | 0.78 | IDO1 (0.57) | KDM4ESMN1; SMN2ALDH1A1MAPK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102939321-B | Stabilized polyene-polythiol curing resin composition | SHOWA DENKO KK | 2014-07-09 | — | — | CN | claimed |
| CN-102939321-A | Stabilized polyene-polythiol curing resin composition | SHOWA DENKO KK | 2013-02-20 | — | — | CN | claimed |
| JP-57095932-A | — | — | None | — | — | JP | disclosed |
| JP-57067530-A | — | — | None | — | — | JP | disclosed |
| JP-9071887-A | — | — | None | — | — | JP | disclosed |
| US-12473248-B2 | Method and intermediate compounds for the preparation of menaquinone MK-7 | VITASYNTH SP. Z.O.O (PL) | 2025-11-18 | — | — | US | disclosed |
| US-20240279184-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | UNIVERSITE DE HAUTE ALSACE (FR) | 2024-08-22 | — | — | US | disclosed |
| US-11827738-B2 | Thiol-ene-curing compositions | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2023-11-28 | — | — | US | disclosed |
| EP-3983385-B1 | NAPHTHOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | PTC THERAPEUTICS INC (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3983385-B1 | NAPHTHOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | PTC THERAPEUTICS INC (US) | 2023-08-30 | — | — | EP | disclosed |
| US-20230250041-A1 | METHOD AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF MENAQUINONE MK-7 | VitaSynth Sp. z.o.o. (PL) | 2023-08-10 | — | — | US | disclosed |
| JP-S5795932-A | PREPARATION OF HYDROQUINONE DERIVATIVE | KURARAY CO LTD | 1982-06-15 | — | — | JP | disclosed |
| JP-S5767530-A | PREPARATION OF HYDROQUINONE DERIVATIVE | KURARAY CO LTD | 1982-04-24 | — | — | JP | disclosed |
| US-4248976-A | COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4234746-A | Metallo-substituted naphthalene | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1980-11-18 | — | — | US | disclosed |
| US-4172858-A | Flame-resistant polymer compositions | CIBA-GEIGY AG (CH) | 1979-10-30 | — | — | US | disclosed |
| US-4159993-A | 3-Metallo substituted naphthalenes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1979-07-03 | — | — | US | disclosed |
| US-4089873-A | Preparation of menaquinones | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1978-05-16 | — | — | US | disclosed |
| US-4060558-A | MULTISTAGE FROM BENZYL HALIDE ALKYLATION OF 1-ACYLATED-1,4-NAPHTHOQUINOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1977-11-29 | — | — | US | disclosed |
| US-3948958-A | Process for making 3-prenylated menaquinones and ether intermediates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473248-B2 | Method and intermediate compounds for the preparation of menaquinone MK-7 | SIRT7, NDUFS7, SDHA | KDM4E 932/4885SMN1; SMN2 3602/4885ALDH1A1 778/4885 |
| US-20230250041-A1 | METHOD AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF MENAQUINONE MK-7 | SIRT7, NDUFS7, SDHA | KDM4E 932/4885SMN1; SMN2 3602/4885ALDH1A1 778/4885 |
| US-20240279184-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CYP1B1, CYP1A1, CYP2B6 | KDM4E 2880/4885SMN1; SMN2 4383/4885ALDH1A1 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.