SCHEMBL106158

SCHEMBL106158

CCCCCCCCCCCCCCCCCCOc1cc(N2C(=O)C(C)C(C)C2=O)cc(N2C(=O)C(C)C(C)C2=O)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PLA2G2A P14555 2/20 0.45
PABPC1 P11940 1/20 0.44
NR5A1 Q13285 1/20 0.42
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HSP90AA1 P07900 1/20 0.41
PLA2G4B P0C869 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
BLM P54132 1/20 0.40
THRA P10827 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105749 0.93 HTT (0.47) HTTLMNASMN1; SMN2PLA2G2APABPC1
SCHEMBL105317 0.81 MGLL (0.54) PLA2G2ANR5A1TSHRTP53PLA2G4B
SCHEMBL13753293 0.79 HTT (0.45) HTTLMNASMN1; SMN2PABPC1NR5A1
SCHEMBL18886699 0.72 PLA2G2A (0.68) HTTLMNASMN1; SMN2PLA2G2ANR5A1
SCHEMBL9016884 0.72 PLA2G2A (0.68) HTTLMNASMN1; SMN2PLA2G2ANR5A1
SCHEMBL2997957 0.69 MGLL (0.62) HTTLMNASMN1; SMN2PABPC1NR5A1
SCHEMBL3003422 0.69 MGLL (0.62) HTTLMNASMN1; SMN2PABPC1NR5A1
SCHEMBL5473083 0.68 NR5A1 (0.79) LMNANR5A1TSHRTP53PLA2G4B
SCHEMBL8936597 0.68 NR5A1 (0.79) LMNANR5A1TSHRTP53PLA2G4B
SCHEMBL11095674 0.68 NR5A1 (0.79) LMNANR5A1TSHRTP53PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120094015-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2012-04-19 US disclosed
US-20120058262-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2012-03-08 US disclosed
US-20090280236-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2009-11-12 US disclosed
US-20090226640-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2009-09-10 US disclosed