Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617168 | 0.91 | ADORA2B (0.49) | ADORA2BADORA2A | |
| SCHEMBL10614242 | 0.89 | ADORA2B (0.53) | ADORA2BADORA2A | |
| SCHEMBL10616213 | 0.84 | PDE5A (0.60) | — | |
| SCHEMBL10614807 | 0.83 | ADORA2B (0.57) | ADORA2B | |
| SCHEMBL4650748 | 0.81 | ADORA2B (0.74) | ADORA2BADORA2A | |
| SCHEMBL10614388 | 0.80 | ADORA2B (0.60) | ADORA2BADORA2A | |
| SCHEMBL10614219 | 0.76 | ADORA2B (0.52) | ADORA2BADORA2A | |
| SCHEMBL10856890 | 0.73 | ADORA2B (0.61) | ADORA2BADORA2A | |
| SCHEMBL10614202 | 0.73 | ADORA2B (0.70) | ADORA2BADORA2A | |
| SCHEMBL10617164 | 0.72 | KDM4E (0.62) | ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769377-A | Adenosine receptor antagonists | THE JOHNS HOPKINS UNIVERSITY (US) | 1988-09-06 | — | — | US | disclosed |