Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 15/20 | 0.91 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651829 | 1.00 | GBA1 (0.91) | GBA1TSHRALDH1A1LMNA | |
| SCHEMBL9481368 | 0.98 | GBA1 (0.87) | GBA1TSHR | |
| SCHEMBL25627228 | 0.98 | GBA1 (0.87) | GBA1TSHRALDH1A1LMNA | |
| SCHEMBL17833025 | 0.95 | GBA1 (1.00) | GBA1TSHR | |
| SCHEMBL3649428 | 0.93 | GBA1 (0.96) | GBA1TSHR | |
| SCHEMBL7750204 | 0.93 | GBA1 (0.95) | GBA1TSHR | |
| SCHEMBL10618513 | 0.91 | GBA1 (0.91) | GBA1TSHRALDH1A1LMNA | |
| SCHEMBL10617470 | 0.91 | GBA1 (0.91) | GBA1TSHRALDH1A1LMNA | |
| SCHEMBL10621226 | 0.91 | GBA1 (0.91) | GBA1TSHRALDH1A1LMNA | |
| SCHEMBL10616769 | 0.91 | GBA1 (0.91) | GBA1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276238-A1 | HEXASUBSTITUTED CYCLOHEXANE COMPOUNDS | MERCK PATENT GmbH (DE) | 1988-08-03 | — | — | EP | disclosed |
| WO-1988000940-A2 | HEXASUBSTITUTED CYCLOHEXANE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-02-11 | — | — | WO | disclosed |