Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619244 | 0.94 | NR3C2 (0.36) | KDM4EALDH1A1HSD17B10NR3C2GAA | |
| SCHEMBL10617286 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL10620352 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10NR3C2GAA | |
| SCHEMBL10621940 | 0.84 | TSHR (0.37) | KDM4EALDH1A1NR3C2HPGDNPSR1 | |
| SCHEMBL10617234 | 0.83 | ALDH1A1 (0.38) | KDM4EALDH1A1HSD17B10NR3C2GAA | |
| SCHEMBL10617810 | 0.79 | TARBP2 (0.45) | KDM4EALDH1A1NR3C2GAAPOLB | |
| SCHEMBL10621777 | 0.78 | ALDH1A1 (0.37) | KDM4EALDH1A1HSD17B10NR3C2GAA | |
| SCHEMBL10617220 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10NR3C2GAA | |
| SCHEMBL10621796 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10617251 | 0.73 | GAA (0.56) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285267-A2 | Pyridine derivatives for treatment and prevention of liver damage, and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |