Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617810 | 0.90 | TARBP2 (0.45) | KDM4EALDH1A1HPGDATMSMN1; SMN2 | |
| SCHEMBL10617220 | 0.89 | KDM4E (0.42) | KDM4EALDH1A1HPGDATMSMN1; SMN2 | |
| SCHEMBL10617162 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1HPGDATMSMN1; SMN2 | |
| SCHEMBL10619244 | 0.86 | NR3C2 (0.36) | KDM4EALDH1A1HPGDATMSMN1; SMN2 | |
| SCHEMBL10621940 | 0.85 | TSHR (0.37) | KDM4EALDH1A1HPGDNR3C2KMT2A | |
| SCHEMBL10617286 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2ABCG2 | |
| SCHEMBL10620227 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDATMSMN1; SMN2 | |
| SCHEMBL10617418 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDATMSMN1; SMN2 | |
| SCHEMBL10617208 | 0.78 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDATMSMN1; SMN2 | |
| SCHEMBL10619132 | 0.77 | HPGD (0.48) | KDM4EALDH1A1HPGDATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285267-A2 | Pyridine derivatives for treatment and prevention of liver damage, and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |