Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620683 | 0.78 | CA1 (0.46) | GAAEGFRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL18175744 | 0.78 | SMN1; SMN2 (0.38) | GAAEGFRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9612024 | 0.74 | RAB9A (0.45) | GAASMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL9313406 | 0.73 | POLB (0.56) | GAASMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL11133278 | 0.73 | CA1 (0.54) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL30827320 | 0.73 | CA1 (0.54) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL6338340 | 0.73 | TSHR (0.48) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL93983 | 0.72 | IDO1 (0.58) | SMN1; SMN2TRPA1POLBCYP1A2MAPT | |
| SCHEMBL10618898 | 0.72 | RAB9A (0.36) | GAAEGFRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11420427 | 0.70 | POLB (0.47) | SMN1; SMN2NPC1RAB9APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083613-B1 | N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | MAY & BAKER LIMITED (GB) | 1988-06-01 | — | — | EP | disclosed |
| US-4496390-A | WEED-CONTRTOLLING HERBICIDES | MAY & BAKER LIMITED (GB) | 1985-01-29 | — | — | US | disclosed |
| US-4459150-A | 5-Acylamino-4-cyano-1-phenylpyrazole derivatives and use as herbicides | MAY & BAKER LIMITED (GB) | 1984-07-10 | — | — | US | disclosed |
| EP-0083613-A1 | N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES. | MAY & BAKER LTD (GB) | 1983-07-20 | — | — | EP | disclosed |
| WO-1983000332-A1 | N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | MAY & BAKER LTD (GB) | 1983-02-03 | — | — | WO | disclosed |