Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.43 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619455 | 1.00 | NFKB1 (0.52) | NFKB1NFKB2RELATRPA1NR4A2 | |
| SCHEMBL10619894 | 0.95 | NFKB1 (0.48) | NFKB1NFKB2RELATRPA1NR4A2 | |
| SCHEMBL10619902 | 0.95 | NFKB1 (0.48) | NFKB1NFKB2RELATRPA1NR4A2 | |
| SCHEMBL10621639 | 0.94 | NFKB1 (0.47) | NFKB1NFKB2RELATRPA1NR4A2 | |
| SCHEMBL10621632 | 0.94 | NFKB1 (0.47) | NFKB1NFKB2RELATRPA1NR4A2 | |
| SCHEMBL10619862 | 0.93 | TRPA1 (0.57) | TRPA1NR4A2HPGDALDH1A1MEN1 | |
| SCHEMBL10619859 | 0.93 | TRPA1 (0.57) | TRPA1NR4A2HPGDALDH1A1MEN1 | |
| SCHEMBL14344308 | 0.93 | TRPA1 (0.57) | TRPA1NR4A2HPGDALDH1A1MEN1 | |
| SCHEMBL30183086 | 0.91 | PTGER3 (0.46) | NFKB1NFKB2RELATRPA1NR4A2 | |
| SCHEMBL10619857 | 0.81 | PTGIR (0.49) | NFKB1NFKB2RELATRPA1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766147-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |