Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6333009 | 0.87 | MEN1 (0.64) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6333011 | 0.87 | MEN1 (0.64) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10618677 | 0.83 | GRM4 (0.58) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| Oxamate SCHEMBL10670122 | 0.80 | KMT2A (0.58) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL27765118 | 0.78 | HDAC1 (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10495641 | 0.73 | APP (0.48) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8523153 | 0.73 | CCNC (0.49) | HDAC6NPC1RAB9ACDK8KDR | |
| SCHEMBL21055912 | 0.73 | CCNC (0.49) | HDAC6NPC1RAB9ACDK8KDR | |
| SCHEMBL10495644 | 0.73 | APP (0.48) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| (Z)-1,2-Diphenylethene SCHEMBL28483617 | 0.71 | HDAC1 (0.61) | ALDH1A1HDAC6MCL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137979-B1 | DIAZINE-ETHENYLPHENYL OXAMIC ACIDS AND ESTERS AND SALTS THEREOF | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1988-10-26 | — | — | EP | claimed |