Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.49 |
| ▸ | CDK8 | P49336 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 4/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523153 | 1.00 | CCNC (0.49) | CCNCCDK8P2RX7HSP90AA1JUN | |
| SCHEMBL25249689 | 0.82 | KDM4E (0.43) | CCNCCDK8P2RX7JUNNFKB1 | |
| SCHEMBL6974319 | 0.82 | KDM4E (0.43) | CCNCCDK8P2RX7JUNNFKB1 | |
| SCHEMBL28060895 | 0.81 | P2RX7 (0.42) | P2RX7HSP90AA1JUNNFKB1PADI4 | |
| Acrylamide SCHEMBL27993614 | 0.78 | P2RX7 (0.40) | CCNCCDK8P2RX7HSP90AA1MKNK1 | |
| SCHEMBL24150077 | 0.77 | CCNC (0.42) | CCNCCDK8P2RX7JUNNFKB1 | |
| SCHEMBL16264150 | 0.75 | JUN (0.46) | P2RX7HSP90AA1JUNNFKB1PADI4 | |
| SCHEMBL3733195 | 0.74 | NPC1 (0.58) | HSP90AA1PADI4NPC1RAB9A | |
| SCHEMBL1382336 | 0.74 | NPC1 (0.58) | HSP90AA1PADI4NPC1RAB9A | |
| SCHEMBL24149768 | 0.74 | APP (0.38) | CCNCCDK8P2RX7JUNNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050880-B1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF CANCER | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2019-06-19 | — | — | EP | disclosed |