Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21578936 | 0.85 | MEN1 (0.47) | NPC1RAB9AKMT2AMAPK1MEN1 | |
| SCHEMBL20391801 | 0.81 | MEN1 (0.45) | NPC1RAB9AKMT2AMAPK1MEN1 | |
| SCHEMBL13699010 | 0.78 | ALDH1A1 (0.53) | MAPK1SLC6A2SLC6A4SLC6A3AKR1C2 | |
| Biphenyl SCHEMBL28360045 | 0.78 | ALDH1A1 (0.53) | MAPK1SLC6A2SLC6A4SLC6A3AKR1C2 | |
| SCHEMBL411336 | 0.78 | ALDH1A1 (0.53) | MAPK1SLC6A2SLC6A4SLC6A3AKR1C2 | |
| SCHEMBL24960564 | 0.78 | MAPK1 (0.42) | NPC1RAB9AKMT2AMAPK1MEN1 | |
| SCHEMBL3793351 | 0.76 | MAOA (0.48) | NPC1RAB9AKMT2AMAPK1MEN1 | |
| SCHEMBL16887401 | 0.75 | ALDH1A1 (0.50) | MAPK1SLC6A2SLC6A4SLC6A3AKR1C2 | |
| SCHEMBL21578555 | 0.75 | ALDH1A1 (0.50) | MAPK1SLC6A2SLC6A4SLC6A3AKR1C2 | |
| SCHEMBL6225564 | 0.75 | TSHR (0.42) | NPC1RAB9AKMT2AMAPK1CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746756-A | Photoconductive imaging members with novel fluorinated squaraine compounds | XEROX CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |
| US-4621038-A | Photoconductive imaging members with novel symmetrical fluorinated squaraine compounds | XEROX CORPORATION (US) | 1986-11-04 | — | — | US | disclosed |