Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 13/20 | 0.83 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAOA | P21397 | 5/20 | 0.64 |
| ▸ | MAOB | P27338 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107428 | 0.94 | ALDH2 (0.90) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL10624579 | 0.92 | ALDH2 (0.86) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL10624708 | 0.91 | ALDH2 (1.00) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL8983972 | 0.89 | MAPT (1.00) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL12940403 | 0.86 | ALDH2 (0.81) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL11551965 | 0.85 | MEN1 (0.75) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL4261437 | 0.83 | MAPT (0.80) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL4095148 | 0.82 | MAPT (0.87) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL10620426 | 0.81 | ALDH1A1 (0.59) | ALDH2MAPTGAAMEN1KMT2A | |
| SCHEMBL11016377 | 0.80 | ALDH2 (0.89) | ALDH2MAPTGAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772627-A | AMORPHOUS DRUG AND ADSORBENT, IMPROVED DISSOLUTION AND ADSORPTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0129893-A2 | Ground mixture | Takeda Chemical Industries, Ltd. (JP) | 1985-01-02 | — | — | EP | disclosed |