SCHEMBL4095148

SCHEMBL4095148

COC(=O)COc1ccc(-c2coc3cc(OCC(=O)OC)ccc3c2=O)cc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.87
ALDH1A1 P00352 3/20 0.87
ALDH2 P05091 10/20 0.71
GAA P10253 1/20 0.69
MAOA P21397 5/20 0.64
MAOB P27338 5/20 0.64
XDH P47989 1/20 0.61
HPGD P15428 2/20 0.60
EGFR P00533 1/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
POLB P06746 1/20 0.60
NPC1 O15118 1/20 0.58
LMNA P02545 1/20 0.58
TSHR P16473 1/20 0.58
MAPK1 P28482 1/20 0.58
RAB9A P51151 1/20 0.58
KDM4E B2RXH2 1/20 0.58
TP53 P04637 1/20 0.58
CYP3A4 P08684 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4261437 0.96 MAPT (0.80) MAPTALDH1A1ALDH2GAAMAOA
SCHEMBL4277128 0.93 MAPT (1.00) MAPTALDH1A1ALDH2GAAMAOA
SCHEMBL2107428 0.88 ALDH2 (0.90) MAPTALDH1A1ALDH2GAAMAOA
SCHEMBL4261439 0.88 MAPT (0.68) MAPTALDH1A1ALDH2GAAMAOA
SCHEMBL4094445 0.86 ALDH2 (0.88) MAPTALDH1A1ALDH2GAAMAOA
SCHEMBL4262292 0.85 MAPT (0.66) MAPTALDH1A1ALDH2GAAXDH
SCHEMBL15341741 0.85 MAPT (0.66) MAPTALDH1A1ALDH2GAAMAOA
SCHEMBL10624579 0.84 ALDH2 (0.86) MAPTALDH1A1ALDH2GAAMAOA
SCHEMBL29036852 0.84 MAPT (0.72) MAPTALDH1A1ALDH2GAAMAOA
SCHEMBL10624708 0.83 ALDH2 (1.00) MAPTALDH1A1ALDH2GAAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-20140099370-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC (US) 2014-04-10 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-8217134-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2012-07-10 US disclosed
US-8217134-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2012-07-10 US disclosed
US-8217134-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2012-07-10 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH MAPT 4117/4885ALDH1A1 1816/4885ALDH2 1402/4885
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM COMT, AOX1, UGT1A6 MAPT 2351/4885ALDH1A1 384/4885ALDH2 1613/4885
US-20140099370-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH MAPT 4117/4885ALDH1A1 1816/4885ALDH2 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.