Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 9/20 | 0.42 |
| ▸ | GABRP | O00591 | 8/20 | 0.42 |
| ▸ | GABRD | O14764 | 8/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.42 |
| ▸ | GABRE | P78334 | 8/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094838 | 0.89 | PTGS1 (0.47) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10618525 | 0.87 | AR (0.37) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11088014 | 0.87 | GABRP (0.40) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11090922 | 0.87 | SMN1; SMN2 (0.50) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11091533 | 0.86 | MAPT (0.39) | CYP3A4ARPTGS1PTGS2ALDH1A1 | |
| SCHEMBL10509024 | 0.86 | PTGS1 (0.36) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11088018 | 0.86 | PTGS1 (0.41) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11092625 | 0.86 | PTGS1 (0.42) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11089201 | 0.84 | PTGS1 (0.40) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11094132 | 0.84 | PTGS1 (0.46) | GABRB3GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459150-A | 5-Acylamino-4-cyano-1-phenylpyrazole derivatives and use as herbicides | MAY & BAKER LIMITED (GB) | 1984-07-10 | — | — | US | claimed |
| EP-0083613-B1 | N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | MAY & BAKER LIMITED (GB) | 1988-06-01 | — | — | EP | disclosed |
| US-4459150-A | 5-Acylamino-4-cyano-1-phenylpyrazole derivatives and use as herbicides | MAY & BAKER LIMITED (GB) | 1984-07-10 | — | — | US | disclosed |
| EP-0083613-A1 | N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES. | MAY & BAKER LTD (GB) | 1983-07-20 | — | — | EP | disclosed |
| WO-1983000332-A1 | N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | MAY & BAKER LTD (GB) | 1983-02-03 | — | — | WO | disclosed |