Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 5/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632059 | 0.96 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1BRD4PDK2PPARG | |
| SCHEMBL10900455 | 0.86 | BRD4 (0.54) | CYSLTR2CYSLTR1BRD4PDK2PPARG | |
| SCHEMBL19510935 | 0.84 | BRD4 (0.55) | CYSLTR2CYSLTR1BRD4PDK2PPARG | |
| SCHEMBL30350748 | 0.84 | BRD4 (0.55) | CYSLTR2CYSLTR1BRD4PDK2PPARG | |
| SCHEMBL30350621 | 0.84 | BRD4 (0.55) | CYSLTR2CYSLTR1BRD4PDK2PPARG | |
| SCHEMBL10080517 | 0.83 | HTT (0.55) | CYSLTR2CYSLTR1BRD4PDE3BPDE3A | |
| SCHEMBL9132945 | 0.82 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1BRD4PDK2PPARG | |
| SCHEMBL767042 | 0.82 | TDP1 (0.62) | CYSLTR2CYSLTR1MAPTLTA4HFAAH | |
| SCHEMBL21533500 | 0.81 | BRD4 (0.64) | CYSLTR2CYSLTR1BRD4PDK2PPARG | |
| SCHEMBL3945405 | 0.81 | HDAC1 (0.61) | PPARGPDE3BPDE3AP2RY12HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4790961-A | CHOLESTERYL ESTERS OF ANTHRACENES AS GELLING AGENTS | GEORGETOWN UNIVERSITY (US) | 1988-12-13 | — | — | US | disclosed |
| WO-1988000938-A1 | THERMALLY REVERSIBLE ORGANIC SOLVENT GELS | GEORGETOWN UNIVERSITY (US) | 1988-02-11 | — | — | WO | disclosed |