Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.64 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620574 | 0.96 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1PPARGBRD4PDK2 | |
| SCHEMBL10900455 | 0.87 | BRD4 (0.54) | CYSLTR2CYSLTR1PPARGBRD4PDK2 | |
| SCHEMBL30350621 | 0.86 | BRD4 (0.55) | CYSLTR2CYSLTR1PPARGBRD4PDK2 | |
| SCHEMBL30350748 | 0.86 | BRD4 (0.55) | CYSLTR2CYSLTR1PPARGBRD4PDK2 | |
| SCHEMBL19510935 | 0.86 | BRD4 (0.55) | CYSLTR2CYSLTR1PPARGBRD4PDK2 | |
| SCHEMBL3945405 | 0.85 | HDAC1 (0.61) | PPARGPDE3BPDE3AP2RY12HDAC1 | |
| SCHEMBL10080517 | 0.85 | HTT (0.55) | CYSLTR2CYSLTR1BRD4PDE3BPDE3A | |
| SCHEMBL9132945 | 0.84 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1PPARGBRD4PDK2 | |
| SCHEMBL27370553 | 0.83 | PTPN7 (0.63) | PPARGPDE3BPDE3AP2RY12MAPT | |
| SCHEMBL767042 | 0.83 | TDP1 (0.62) | CYSLTR2CYSLTR1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790260-B1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5902765-A | MADE BY REACTING A MAGNESIUM DIHALIDE WITH TETRAHYDROFURAN, BUTYL ETHER OR DIETHYL ETHER AND TREATING THE SOLID SUBSTANCE WITH AN ELECTRON DONATIVE COMPOUND HAVING TWO OR MORE ALKOXY OR ESTER GROUPS, CONTACTING WITH TITANIUM; STEREOREGULARITY | JAPAN POLYOLEFINS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0790260-A1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |