SCHEMBL10620607

SCHEMBL10620607

O=C(O)C(O)C(O)(C(=O)O)C(O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CPT2 P23786 1/20 0.48
ACLY P53396 1/20 0.48
TSHR P16473 3/20 0.37
ALDH1A1 P00352 3/20 0.35
TP53 P04637 2/20 0.35
OR51E2 Q9H255 1/20 0.30
LMNA P02545 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11797107 0.86 CPT2 (0.43) CPT2ACLYTSHRALDH1A1TP53
SCHEMBL2815553 0.84 CPT2 (0.41) CPT2ACLYTSHRALDH1A1TP53
SCHEMBL7650264 0.78 CPT2 (0.38) CPT2ACLYTSHRALDH1A1TP53
SCHEMBL27817893 0.77 CPT2 (0.44) CPT2ACLYTSHRALDH1A1TP53
SCHEMBL28720884 0.77 CPT2 (0.36) CPT2ACLY
SCHEMBL736499 0.75 CPT2 (0.48) CPT2ACLYTSHRALDH1A1TP53
SCHEMBL28472849 0.75 CPT2 (0.39) CPT2ACLY
SCHEMBL721349 0.75 CPT2 (0.48) CPT2ACLYTSHRALDH1A1TP53
SCHEMBL27782158 0.73 LMNA (0.47) LMNA
SCHEMBL28262205 0.73 LMNA (0.47) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4774138-A DIOL AND HYDROXY DI-OR-TRI-CARBOXYLIC ACID HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-09-27 US claimed
CN-118165141-A Chitosan-tricarboxylic acid derivative and preparation method and application thereof 珠海市自然之旅生物技术有限公司 2024-06-11 CN disclosed
CN-116162181-B Chitosan-tricarboxylic acid derivative and preparation method and application thereof 珠海市自然之旅生物技术有限公司 2024-04-12 CN disclosed
CN-116549427-B Application of hydroxycitric acid lactone in preparation of medicine for treating gall-stone 时珍本草生物科技(中山)有限公司 2024-01-26 CN disclosed
CN-116549427-A New use of hydroxycitric acid for treating cholelithiasis and cholecystitis induced by cholelithiasis 时珍本草生物科技(中山)有限公司 2023-08-08 CN disclosed
CN-116162181-A Chitosan-tricarboxylic acid derivative and preparation method and application thereof 珠海市自然之旅生物技术有限公司 2023-05-26 CN disclosed
CN-101330911-A Hydroxy-polycarboxylic acid esters: action on nerves and use on skin and mucocutaneous organs or sites SCOTT EUGENE J VAN (US) 2008-12-24 CN disclosed
US-4774138-A DIOL AND HYDROXY DI-OR-TRI-CARBOXYLIC ACID HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-09-27 US disclosed
US-4645537-A MIXTURE OF DIHYDROXY ALIPHATIC ALCOHOL, AND ALIPHATIC HYDROXY DI-(OR TRI-) CARBOXYLIC ACID HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-02-24 US disclosed
US-4576835-A POLYHYDRIC ALIPHATIC ALCOHOL, ALIPHATIC POLYCARBOXYLIC ACID OR SALT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-03-18 US disclosed