Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618160 | 0.85 | PLA2G7 (0.38) | PLA2G7 | |
| SCHEMBL7012765 | 0.83 | PLA2G7 (0.53) | PLA2G7 | |
| SCHEMBL10618122 | 0.83 | PLA2G7 (0.34) | PLA2G7GAA | |
| SCHEMBL10847559 | 0.83 | PLA2G7 (0.35) | PLA2G7 | |
| SCHEMBL7741650 | 0.82 | PLA2G7 (0.43) | PLA2G7GAA | |
| SCHEMBL10653869 | 0.82 | PLA2G7 (0.46) | PLA2G7 | |
| SCHEMBL10848628 | 0.82 | PLA2G7 (0.33) | PLA2G7 | |
| SCHEMBL7743913 | 0.81 | PLA2G7 (0.36) | PLA2G7 | |
| SCHEMBL10618958 | 0.81 | PLA2G7 (0.48) | PLA2G7 | |
| SCHEMBL10651417 | 0.79 | PLA2G7 (0.36) | PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083186-B1 | THIAZOLE DERIVATIVES AS H2-RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1988-05-11 | — | — | EP | disclosed |
| EP-0113572-B1 | PYRIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-02-03 | — | — | EP | disclosed |
| EP-0112707-B1 | AMINOPYRIMIDINONE DERIVATIVES AS HISTAMINE H1-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4665078-A | RHINITIS, HAY FEVER, ASTHMA, ECZEMA | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-05-12 | — | — | US | disclosed |
| US-4652650-A | Pyridylaminoalkylamine intermediates | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-03-24 | — | — | US | disclosed |
| US-4649141-A | HISTAMINE ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-03-10 | — | — | US | disclosed |
| US-4639519-A | 2-substituted alkylaminopyrimidones useful as H2 -antagonists and antiinflamatory agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-01-27 | — | — | US | disclosed |
| EP-0068833-B1 | PYRIMIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-10-15 | — | — | EP | disclosed |
| EP-0068834-B1 | PYRIMIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-09-03 | — | — | EP | disclosed |
| US-4607107-A | CHEMICAL INTERMEDIATES FOR HESTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1986-08-19 | — | — | US | disclosed |
| US-4234588-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-11-18 | — | — | US | disclosed |
| EP-0017679-A1 | Pyridylalkylpyrimidone compounds, process for preparing them and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-29 | — | — | EP | disclosed |
| EP-0017680-A1 | Pyrimidone derivatives, process for preparing them and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-29 | — | — | EP | disclosed |
| US-4227000-A | Intermediates in the process for making histamine antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-07 | — | — | US | disclosed |
| EP-0015138-A1 | Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-09-03 | — | — | EP | disclosed |
| EP-0013071-A1 | Pyrimidinone derivatives, processes for preparing them and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-07-09 | — | — | EP | disclosed |
| WO-1980000966-A1 | NEW HISTAMINE H2-ANTAGONISTS | SMITH KLINE FRENCH LAB (GB) | 1980-05-15 | — | — | WO | disclosed |
| EP-0007232-A1 | Iso(thio)ureas, processes for their preparation and compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-01-23 | — | — | EP | disclosed |
| EP-0004793-A2 | 2-nitro aminopyrimidone derivatives, a process for their preparation and their use to prepare 2-aminopyrimidone derivatives which have histamine H2-antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-17 | — | — | EP | disclosed |
| EP-0003677-A2 | Pyrimidones, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |