Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001555 | 0.82 | PLA2G7 (0.37) | PLA2G7 | |
| SCHEMBL10620753 | 0.81 | PLA2G7 (0.51) | PLA2G7 | |
| SCHEMBL10651417 | 0.80 | PLA2G7 (0.36) | PLA2G7 | |
| SCHEMBL10653869 | 0.78 | PLA2G7 (0.46) | PLA2G7 | |
| SCHEMBL10848628 | 0.78 | PLA2G7 (0.33) | PLA2G7 | |
| SCHEMBL10734841 | 0.78 | L3MBTL1 (0.34) | PLA2G7L3MBTL1 | |
| SCHEMBL10656049 | 0.78 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL10618958 | 0.77 | PLA2G7 (0.48) | PLA2G7 | |
| SCHEMBL10618122 | 0.77 | PLA2G7 (0.34) | PLA2G7 | |
| SCHEMBL10618160 | 0.76 | PLA2G7 (0.38) | PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417192-B1 | DRUGS WITH PYRIMIDONE COMPOUNDS INHIBITORS OF THE ENZYME LDL PLA.SUB.2 AND THEREFORE OF USE IN TREATING ATHEROSCLEROSIS. | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-07-09 | — | — | US | disclosed |
| EP-0112707-B1 | AMINOPYRIMIDINONE DERIVATIVES AS HISTAMINE H1-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4652650-A | Pyridylaminoalkylamine intermediates | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-03-24 | — | — | US | disclosed |
| US-4639519-A | 2-substituted alkylaminopyrimidones useful as H2 -antagonists and antiinflamatory agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-01-27 | — | — | US | disclosed |
| EP-0068833-B1 | PYRIMIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-10-15 | — | — | EP | disclosed |
| EP-0068834-B1 | PYRIMIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-09-03 | — | — | EP | disclosed |
| US-4584381-A | HISTAMINE H1-ANTAGONIST | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-04-22 | — | — | US | disclosed |
| US-4558128-A | ANTIHISTAMINE, ANTIINFLAMMATORY AGENT | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-12-10 | — | — | US | disclosed |
| US-4548940-A | Pyridylaminoalkylaminopyrimidones useful as histamine H1 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-10-22 | — | — | US | disclosed |
| US-4535163-A | ANTIHISTAMINES; PYRIMIDONE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-08-13 | — | — | US | disclosed |
| US-4444772-A | 2-(3,5-DISUBSTITUTED-PYRIDYLALKYLAMINO)-5-PYRIDYLMETHYL-4 -PYRIMIDONE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-04-24 | — | — | US | disclosed |
| US-4439435-A | PYRIMIDONE OR PYRIMID-THIONE DERIVATIVES, HISTAMINE ANTAGONIST, ANTIINFLAMMATORY | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1984-03-27 | — | — | US | disclosed |
| EP-0015138-B1 | PYRIMIDONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-03-16 | — | — | EP | disclosed |
| EP-0068834-A2 | Pyrimidinone derivatives and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-01-05 | — | — | EP | disclosed |
| EP-0068833-A2 | Pyrimidinone derivatives and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-01-05 | — | — | EP | disclosed |
| EP-0017680-B1 | PYRIMIDONE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1982-04-21 | — | — | EP | disclosed |
| US-4305945-A | Isoureas and isothioureas | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-15 | — | — | US | disclosed |
| EP-0017680-A1 | Pyrimidone derivatives, process for preparing them and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-29 | — | — | EP | disclosed |
| EP-0015138-A1 | Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-09-03 | — | — | EP | disclosed |
| EP-0007232-A1 | Iso(thio)ureas, processes for their preparation and compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-01-23 | — | — | EP | disclosed |